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Available in 90, 180, or 270 Softgels (1-3 Month Supply)
DE3 Dry Eye Omega Benefits® is a high-potency, clinically proven omega-3 supplement designed to support healthy tear production and improve occasional dry eye symptoms such as grittiness, dryness, and burning.
Take three softgels daily with a meal, or as directed by your healthcare professional.
The American Heart Association and American Cardiology Association recommend 2-3 grams of omega-3s daily (EPA + DHA). To match the omega-3 levels in DE3 (3 softgels/day), you’d need to consume 37 cans of tuna per week—posing a high risk of mercury poisoning.
Flaxseed provides alpha-linolenic acid (ALA), a plant-based omega-3 that is far less bioavailable than marine-based omega-3s (EPA & DHA). Marine omega-3s are up to 10x more effective for supporting eye health.
DE3 uses an ultra-purified, triglyceride (rTG) form of omega-3s—identical to the form found in fresh fish but without impurities. Most store-bought omega-3s contain low doses of EPA & DHA in synthetic forms that are harder for the body to absorb and often cause a fishy aftertaste.
¹ Epitropoulos, Alice T. et al., Effect of Oral Re-esterified Omega-3 Nutritional Supplementation on Dry Eyes. Cornea 2016.
* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Fast, tracked delivery
Your order typically arrives within 3–5 business days within the contiguous US, with tracking included on every shipment.
Easy 30-day returns
Changed your mind? Return unopened items in their original packaging within 30 days for a refund to your original payment method.
Some items are final sale
For health and safety, opened prescription products and contact lenses can't be returned.

$128.95
Works foe Me
I began taking Dryeye Fishoil after I had eye surgery. While it helped my dry eye, the biggest surprise came when my cholesterol, triglyceride, and A1C numbers began to drop. I found this quality fish oil help make my body better able to use the meds I was taking. My primary physician believes this fish oil has made a big difference and encourages me to continue taking it.
Great supplement
Great supplement. I like that it also has vitamin DE3 with the Omega. My eye doctor recommended.
Pills are very big
Pills are very big and dose is 3. Hard to swallow
Dry Eye Rescue
I'm really liking how these are helping with my dry eyes!
Excellent Product
I’ve been using this supplement for over a year and it truly stands up to its promise .
It seems to work but for seniors on a limited budget it's too expensive.
If you truly wanted to help people with dry eye issues you would make the product affordable to those like me (senior - 77) on a limited budget. You have to purchase this product every month because it only lasts for a month and it's over $70. Who can afford that.
PRN DE3 Dry Eye Omega Benefits
I believe these are doing me a very great help with my dry eyes!
Dry eye
Seems to be helping some,
De3
absolutely life changing the internal eye pain gone with first month and headaches reduced to 1-2 times in that month!
Good product
High in DHA and EPA important. A little pricey though.
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